BDBM50142846 (S)-2-[(R)-(6-Bromo-naphthalen-2-yl)-methoxycarbonyl-methyl]-pyrrolidinium; chloride::CHEMBL301830

SMILES COC(=O)[C@@H]([C@@H]1CCC[NH2+]1)c1ccc2cc(Br)ccc2c1

InChI Key InChIKey=CEWOEUHWHFEXBY-UHFFFAOYSA-O

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142846   

TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50142846((S)-2-[(R)-(6-Bromo-naphthalen-2-yl)-methoxycarbon...)
Affinity DataIC50: 446nMAssay Description:Inhibitory activity against dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50142846((S)-2-[(R)-(6-Bromo-naphthalen-2-yl)-methoxycarbon...)
Affinity DataIC50: 446nMAssay Description:Potency of inhibiting 10 pM [125I]RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50142846((S)-2-[(R)-(6-Bromo-naphthalen-2-yl)-methoxycarbon...)
Affinity DataKi:  5.5nMAssay Description:Ability to displace 0.4 nM [3H]paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50142846((S)-2-[(R)-(6-Bromo-naphthalen-2-yl)-methoxycarbon...)
Affinity DataKi:  5.5nMAssay Description:Ability to displace 0.4 nM [3H]paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed