BDBM50142847 (R)-2-((S)-Methoxycarbonyl-naphthalen-2-yl-methyl)-pyrrolidinium; chloride::CHEMBL51264

SMILES COC(=O)[C@H]([C@H]1CCC[NH2+]1)c1ccc2ccccc2c1

InChI Key InChIKey=NHOGTKAKJAXBLQ-UHFFFAOYSA-O

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142847   

TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50142847((R)-2-((S)-Methoxycarbonyl-naphthalen-2-yl-methyl)...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibitory activity against dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50142847((R)-2-((S)-Methoxycarbonyl-naphthalen-2-yl-methyl)...)
Affinity DataKi:  2.02E+3nMAssay Description:Ability to displace 0.4 nM [3H]paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed