BDBM50142854 (R)-2-((R)-Methoxycarbonyl-phenyl-methyl)-pyrrolidinium; chloride::CHEMBL50193

SMILES COC(=O)[C@@H]([C@H]1CCC[NH2+]1)c1ccccc1

InChI Key InChIKey=IDFZQTFWJZUVDF-UHFFFAOYSA-O

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142854   

TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50142854((R)-2-((R)-Methoxycarbonyl-phenyl-methyl)-pyrrolid...)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibitory activity against dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50142854((R)-2-((R)-Methoxycarbonyl-phenyl-methyl)-pyrrolid...)
Affinity DataIC50: 3.16E+3nMAssay Description:Potency of inhibiting 10 pM [125I]RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50142854((R)-2-((R)-Methoxycarbonyl-phenyl-methyl)-pyrrolid...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace 0.4 nM [3H]paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed