BDBM50142856 (R)-2-[(R)-(4-Chloro-phenyl)-methoxycarbonyl-methyl]-pyrrolidinium; chloride::CHEMBL300656

SMILES COC(=O)[C@@H]([C@H]1CCC[NH2+]1)c1ccc(Cl)cc1

InChI Key InChIKey=PNQATGDUZVMRRR-UHFFFAOYSA-O

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142856   

TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50142856((R)-2-[(R)-(4-Chloro-phenyl)-methoxycarbonyl-methy...)
Affinity DataIC50: 272nMAssay Description:Inhibitory activity against dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50142856((R)-2-[(R)-(4-Chloro-phenyl)-methoxycarbonyl-methy...)
Affinity DataKi:  1.08E+3nMAssay Description:Ability to displace 0.4 nM [3H]paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed