BDBM50142882 Butyl-[1-(2-chloro-2-phenyl-ethyl)-6-ethylsulfanyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-amine::CHEMBL41910::N-butyl-1-(2-chloro-2-phenylethyl)-6-(ethylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

SMILES CCCCNc1nc(SCC)nc2n(CC(Cl)c3ccccc3)ncc12

InChI Key InChIKey=RIIKNMAPWOLEED-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142882   

TargetTyrosine-protein kinase ABL1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50142882(N-butyl-1-(2-chloro-2-phenylethyl)-6-(ethylthio)-1...)
Affinity DataKi:  320nMAssay Description:Inhibition of recombinant wild type c-ABL (unknown origin) after 5 mins by scintillation counting analysis in presence of [gamma32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50142882(N-butyl-1-(2-chloro-2-phenylethyl)-6-(ethylthio)-1...)
Affinity DataKi:  600nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50142882(N-butyl-1-(2-chloro-2-phenylethyl)-6-(ethylthio)-1...)
Affinity DataKi:  631nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed