BDBM50142997 (S)-2-[(4-Chloro-phenyl)-phenyl-methoxymethyl]-8-methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane; hydrochloride::CHEMBL537994

SMILES CN1C2CCC1[C@@H](COC(c1ccccc1)c1ccc(Cl)cc1)C(C2)c1ccc(C)cc1

InChI Key InChIKey=SWUYKZCLBQJENR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142997   

TargetSodium-dependent dopamine transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50142997((S)-2-[(4-Chloro-phenyl)-phenyl-methoxymethyl]-8-m...)
Affinity DataKi:  80nMAssay Description:Binding affinity against dopamine transporter by using [3H]WIN-35428 as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50142997((S)-2-[(4-Chloro-phenyl)-phenyl-methoxymethyl]-8-m...)
Affinity DataKi:  443nMAssay Description:Binding affinity against serotonin transporter by using [3H]-citalopram as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50142997((S)-2-[(4-Chloro-phenyl)-phenyl-methoxymethyl]-8-m...)
Affinity DataKi:  4.40E+3nMAssay Description:Binding affinity against norepinephrine transporter by using [3H]nisoxetine as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50142997((S)-2-[(4-Chloro-phenyl)-phenyl-methoxymethyl]-8-m...)
Affinity DataKi:  3.16E+4nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor M1 by using [3H]pirenzepine as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed