BDBM50143062 CHEMBL3758435

SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccc(F)cc2C1=O

InChI Key InChIKey=VFXGJBMGVJCVPD-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50143062   

TargetCytochrome P450 1A2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50143062(CHEMBL3758435)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50143062(CHEMBL3758435)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50143062(CHEMBL3758435)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50143062(CHEMBL3758435)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50143062(CHEMBL3758435)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu5 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50143062(CHEMBL3758435)
Affinity DataEC50:  1.93E+4nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50143062(CHEMBL3758435)
Affinity DataEC50:  1.93E+4nMAssay Description:Positive allosteric modulation of human mGlu1 receptor by cell based calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed