BDBM50143455 (S)-2-((S)-2-{3-Benzyl-3-[(2R,3S)-3-((S)-2-tert-butoxycarbonylamino-3-phenyl-propionylamino)-2-hydroxy-4-phenyl-butyl]-ureido}-4-methyl-pentanoylamino)-3-methyl-butyric acid methyl ester::CHEMBL367743
SMILES COC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)N(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1)C(C)C
InChI Key InChIKey=FCGCXNCKEPAINT-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50143455
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of amyloid-beta production in Chinese hamster ovary (CHO) cells expressing human amyloid precursor protein (APP)More data for this Ligand-Target Pair