BDBM50143603 11-amino-4-methyl-(1S,5R,16R,17S)-15-oxa-10-thia-4,12-diazahexacyclo[12.6.1.01,16.05,20.07,21.09,13]henicosa-7(21),8,11,13-tetraen-17-ol::CHEMBL294168

SMILES CN1CC[C@@]23C4Oc5c2c(C[C@@H]1C3CC[C@@H]4O)cc1sc(N)nc51

InChI Key InChIKey=KKRYMNWLKBTOGZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50143603   

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143603(11-amino-4-methyl-(1S,5R,16R,17S)-15-oxa-10-thia-4...)
Affinity DataKi:  30nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143603(11-amino-4-methyl-(1S,5R,16R,17S)-15-oxa-10-thia-4...)
Affinity DataKi:  32nMAssay Description:Inhibition of [3H]naltrindole binding to opioid receptor delta 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143603(11-amino-4-methyl-(1S,5R,16R,17S)-15-oxa-10-thia-4...)
Affinity DataKi:  220nMAssay Description:Agonistic activity against kappa opioid receptor in Chinese hamster ovary membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed