BDBM50143608 20-methyl-(1R,12R)-7-thia-5,20-diazapentacyclo[10.5.3.01,13.02,10.04,8]icosa-2(10),3,5,8-tetraen-6-amine::CHEMBL56360

SMILES CN1CC[C@]23CCCCC2[C@H]1Cc1cc2sc(N)nc2cc31

InChI Key InChIKey=MFCKRIRSBAZCHR-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50143608   

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143608(20-methyl-(1R,12R)-7-thia-5,20-diazapentacyclo[10....)
Affinity DataKi:  1.10nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143608(20-methyl-(1R,12R)-7-thia-5,20-diazapentacyclo[10....)
Affinity DataKi:  1.10nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143608(20-methyl-(1R,12R)-7-thia-5,20-diazapentacyclo[10....)
Affinity DataKi:  29nMAssay Description:Agonistic activity against kappa opioid receptor in Chinese hamster ovary membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143608(20-methyl-(1R,12R)-7-thia-5,20-diazapentacyclo[10....)
Affinity DataKi:  29nMAssay Description:Inhibition of [3H]U-69593 binding to Opioid receptor kappa 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143608(20-methyl-(1R,12R)-7-thia-5,20-diazapentacyclo[10....)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of [3H]naltrindole binding to opioid receptor delta 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed