BDBM50143611 13-cyclobutylmethyl-1,16-dimethyl-(1R,12R,16R)-7-thia-5,13-diazatetracyclo[10.3.1.02,10.04,8]hexadeca-2(10),3,5,8-tetraen-6-amine::CHEMBL301701

SMILES C[C@H]1[C@H]2Cc3cc4sc(N)nc4cc3[C@]1(C)CCN2CC1CCC1

InChI Key InChIKey=DARNEFFTPDYZKR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50143611   

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143611(13-cyclobutylmethyl-1,16-dimethyl-(1R,12R,16R)-7-t...)
Affinity DataKi:  0.490nMAssay Description:Agonistic activity against kappa opioid receptor in Chinese hamster ovary membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143611(13-cyclobutylmethyl-1,16-dimethyl-(1R,12R,16R)-7-t...)
Affinity DataKi:  8.30nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50143611(13-cyclobutylmethyl-1,16-dimethyl-(1R,12R,16R)-7-t...)
Affinity DataKi:  93nMAssay Description:Inhibition of [3H]naltrindole binding to opioid receptor delta 1 of Chinese hamster ovary membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed