BDBM50143658 2-{4-[2-(7,9-Dioxo-8-aza-spiro[4.5]dec-8-yl)-ethyl]-piperazin-1-yl}-benzonitrile::CHEMBL299022
SMILES O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(CC1)c1ccccc1C#N
InChI Key InChIKey=FIKCUNQQOIUGKX-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50143658
Affinity DataKi: 0.930nMAssay Description:Binding affinity to the adrenergic receptor alpha-1D of rat aortaMore data for this Ligand-Target Pair
Affinity DataKi: 5.37nMAssay Description:Binding affinity to human 5-hydroxytryptamine 1A receptor was measured using [3H]-8-hydroxy-2-(di-n-propylamine) tetraline [3H]8-OH-DPAT) as radiolig...More data for this Ligand-Target Pair
Affinity DataKi: 46.2nMAssay Description:Binding affinity constant against alpha-1B adrenergic receptor of guinea pig spleenMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Binding affinity to adrenergic alpha1A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 171nMAssay Description:Binding affinity to adrenergic alpha1A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 214nMAssay Description:In vitro binding affinity towards alpha-1A adrenergic receptor through displacement of [3H]prazosin in epididymal rat vas deferens.More data for this Ligand-Target Pair