BDBM50143965 CHEMBL60666::N-(2-{4-[3-(4-Chloro-phenoxy)-2-hydroxy-propyl]-piperazin-1-yl}-2-phenyl-ethyl)-2-methoxy-benzamide

SMILES COc1ccccc1C(=O)NCC(N1CCN(CC(O)COc2ccc(Cl)cc2)CC1)c1ccccc1

InChI Key InChIKey=MAHIHXILBQDWFG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143965   

LigandPNGBDBM50143965(N-(2-{4-[3-(4-Chloro-phenoxy)-2-hydroxy-propyl]-pi...)
Affinity DataIC50: 363nMAssay Description:In vitro inhibition of [3H]batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50143965(N-(2-{4-[3-(4-Chloro-phenoxy)-2-hydroxy-propyl]-pi...)
Affinity DataKi:  7.00E+3nMAssay Description:Predictive competitive inhibition of cytochrome P450 2D6 was determined in silicoMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed