BDBM50144147 CHEMBL65868::N-(1-Methoxy-6-p-tolyl-6H-benzo[c]chromen-8-yl)-methanesulfonamide

SMILES COc1cccc2OC(c3ccc(C)cc3)c3cc(NS(C)(=O)=O)ccc3-c12

InChI Key InChIKey=PCEQNBCVZPRGRR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50144147   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144147(N-(1-Methoxy-6-p-tolyl-6H-benzo[c]chromen-8-yl)-me...)
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR); Value ranges from 6-7 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144147(N-(1-Methoxy-6-p-tolyl-6H-benzo[c]chromen-8-yl)-me...)
Affinity DataIC50: 651nMAssay Description:Displacement of [3H]aldosterone from human Mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144147(N-(1-Methoxy-6-p-tolyl-6H-benzo[c]chromen-8-yl)-me...)
Affinity DataIC50: 673nMAssay Description:Displacement of [3H]progesterone from human Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144147(N-(1-Methoxy-6-p-tolyl-6H-benzo[c]chromen-8-yl)-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]estradiol from human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144147(N-(1-Methoxy-6-p-tolyl-6H-benzo[c]chromen-8-yl)-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]mibolerone from human Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed