BDBM50144191 CHEMBL61954::Dicyclopropylmethyl-[4-(2,4-dimethoxy-6-methyl-phenyl)-5-methyl-pyrimidin-2-yl]-propyl-amine

SMILES CCCN(C(C1CC1)C1CC1)c1ncc(C)c(n1)-c1c(C)cc(OC)cc1OC

InChI Key InChIKey=BKMXDBDJIKZXQU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144191   

TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50144191(Dicyclopropylmethyl-[4-(2,4-dimethoxy-6-methyl-phe...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards human Corticotropin releasing factor receptor 1 by the displacement of [125I]CRF from CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed