BDBM50144219 CHEMBL3758225

SMILES COc1ccc2ccc3occ(CNC(C)=O)c3c2c1

InChI Key InChIKey=QPKNKIVHVXHLQH-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50144219   

TargetMelatonin receptor type 1B(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50144219(CHEMBL3758225)
Affinity DataKi:  0.700nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50144219(CHEMBL3758225)
Affinity DataEC50:  1.40nMAssay Description:Intrinsic activity at human MT2 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50144219(CHEMBL3758225)
Affinity DataKi:  4.60nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cell membranes after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50144219(CHEMBL3758225)
Affinity DataEC50:  4.80nMAssay Description:Intrinsic activity at human MT1 receptor expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50144219(CHEMBL3758225)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details Article
PubMed