BDBM50144669 2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl)-3-(4-methanesulfonylamino-benzyloxythiocarbonylamino)-propyl ester::CHEMBL308589

SMILES Cc1ccc(CC(CNC(=S)OCc2ccc(NS(C)(=O)=O)cc2)COC(=O)C(C)(C)C)cc1C

InChI Key InChIKey=BGGGXHNSURQXCK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144669   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50144669(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  336nMAssay Description:Agonist effect on 45 [Ca2+] influx in vanilloid receptor expressing CHO cells relative to maximal capsaicin (300 nM) responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50144669(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataIC50: 440nMAssay Description:In vitro antagonist effect against 50 nM capsaicin-induced 45 [Ca2+] influx in vanilloid receptor expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed