BDBM50144771 3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazin-7-ol::CHEMBL74757

SMILES CC1Oc2cc(O)ccc2N=C1c1ccc(O)cc1

InChI Key InChIKey=LBUVQMLHJOQGMT-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50144771   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144771(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazin-...)
Affinity DataEC50:  30nMAssay Description:Ability to activate estrogen receptor 2-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144771(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazin-...)
Affinity DataEC50:  64nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144771(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazin-...)
Affinity DataIC50: 330nMAssay Description:Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144771(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazin-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Binding affinity towards estrogen receptor alpha by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed