BDBM50144773 3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine-5,7-diol::CHEMBL264862

SMILES CC1Oc2cc(O)cc(O)c2N=C1c1ccc(O)cc1

InChI Key InChIKey=LIEZHLXUCGSNOU-UHFFFAOYSA-N

Data  6 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50144773   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144773(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine...)
Affinity DataEC50:  47nMAssay Description:Ability to activate estrogen receptor 2-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144773(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine...)
Affinity DataEC50:  50nMAssay Description:Ability to activate estrogen receptor 2-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144773(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine...)
Affinity DataEC50:  50nMAssay Description:Ability to activate estrogen receptor 2-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144773(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine...)
Affinity DataEC50:  140nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144773(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine...)
Affinity DataEC50:  140nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144773(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine...)
Affinity DataEC50:  150nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144773(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine...)
Affinity DataIC50: 240nMAssay Description:Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144773(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine...)
Affinity DataIC50: 240nMAssay Description:Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144773(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine...)
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144773(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine...)
Affinity DataIC50: 2.80E+3nMAssay Description:Binding affinity towards estrogen receptor alpha by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144773(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine...)
Affinity DataIC50: 2.80E+3nMAssay Description:Binding affinity towards estrogen receptor alpha by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144773(3-(4-Hydroxy-phenyl)-2-methyl-2H-benzo[1,4]oxazine...)
Affinity DataIC50: 2.90E+3nMAssay Description:Binding affinity towards estrogen receptor alpha by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed