BDBM50144774 3-(3-Bromo-4-hydroxy-phenyl)-2,2-dimethyl-2H-benzo[1,4]oxazine-5,7-diol::CHEMBL74027

SMILES CC1(C)Oc2cc(O)cc(O)c2N=C1c1ccc(O)c(Br)c1

InChI Key InChIKey=OGSCAUAIMGNCAJ-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50144774   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144774(3-(3-Bromo-4-hydroxy-phenyl)-2,2-dimethyl-2H-benzo...)
Affinity DataEC50:  120nMAssay Description:Ability to activate estrogen receptor 2-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144774(3-(3-Bromo-4-hydroxy-phenyl)-2,2-dimethyl-2H-benzo...)
Affinity DataEC50:  1.40E+3nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144774(3-(3-Bromo-4-hydroxy-phenyl)-2,2-dimethyl-2H-benzo...)
Affinity DataIC50: 1.70E+3nMAssay Description:Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144774(3-(3-Bromo-4-hydroxy-phenyl)-2,2-dimethyl-2H-benzo...)
Affinity DataIC50: 6.00E+3nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed