BDBM50144782 3-(4-Hydroxy-phenyl)-2H-benzo[1,4]oxazine-5,7-diol::CHEMBL74022

SMILES Oc1ccc(cc1)C1=Nc2c(O)cc(O)cc2OC1

InChI Key InChIKey=VQDBCOBHKZQZJK-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50144782   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144782(3-(4-Hydroxy-phenyl)-2H-benzo[1,4]oxazine-5,7-diol...)
Affinity DataEC50:  270nMAssay Description:Ability to activate estrogen receptor 2-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144782(3-(4-Hydroxy-phenyl)-2H-benzo[1,4]oxazine-5,7-diol...)
Affinity DataEC50:  1.80E+3nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144782(3-(4-Hydroxy-phenyl)-2H-benzo[1,4]oxazine-5,7-diol...)
Affinity DataIC50: 2.80E+3nMAssay Description:Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144782(3-(4-Hydroxy-phenyl)-2H-benzo[1,4]oxazine-5,7-diol...)
Affinity DataIC50: 3.30E+4nMAssay Description:Binding affinity towards estrogen receptor alpha by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed