BDBM50144784 10a,11-Dihydro-10-oxa-5-aza-benzo[b]fluorene-2,8-diol::CHEMBL73989

SMILES Oc1ccc2C3=Nc4ccc(O)cc4OC3Cc2c1

InChI Key InChIKey=BBAHLFZPNXNEGK-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50144784   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144784(10a,11-Dihydro-10-oxa-5-aza-benzo[b]fluorene-2,8-d...)
Affinity DataEC50:  77nMAssay Description:Ability to activate estrogen receptor 2-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144784(10a,11-Dihydro-10-oxa-5-aza-benzo[b]fluorene-2,8-d...)
Affinity DataEC50:  900nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144784(10a,11-Dihydro-10-oxa-5-aza-benzo[b]fluorene-2,8-d...)
Affinity DataIC50: 1.40E+3nMAssay Description:Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144784(10a,11-Dihydro-10-oxa-5-aza-benzo[b]fluorene-2,8-d...)
Affinity DataIC50: 5.60E+3nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed