BDBM50144785 3-(4-Hydroxy-phenyl)-2,2-dimethyl-2H-benzo[1,4]oxazin-7-ol::CHEMBL307205

SMILES CC1(C)Oc2cc(O)ccc2N=C1c1ccc(O)cc1

InChI Key InChIKey=LLSQLACTSVIXID-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50144785   

TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144785(3-(4-Hydroxy-phenyl)-2,2-dimethyl-2H-benzo[1,4]oxa...)
Affinity DataEC50:  140nMAssay Description:Ability to activate estrogen receptor 2-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144785(3-(4-Hydroxy-phenyl)-2,2-dimethyl-2H-benzo[1,4]oxa...)
Affinity DataEC50:  3.10E+3nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144785(3-(4-Hydroxy-phenyl)-2,2-dimethyl-2H-benzo[1,4]oxa...)
Affinity DataIC50: 5.60E+3nMAssay Description:Binding affinity towards estrogen receptor beta by [3H]17-beta-estradiol displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50144785(3-(4-Hydroxy-phenyl)-2,2-dimethyl-2H-benzo[1,4]oxa...)
Affinity DataIC50: 8.60E+3nMAssay Description:Ability to activate estrogen receptor 1-mediated transcription.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed