BDBM50144882 CHEMBL266288

SMILES CSCC[C@@H]1NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]2CSSSSC[C@@H]3NC(=O)[C@@H]4CCCN4C(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]4CSSSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CSSSSC[C@H](NC(=O)[C@@H]5CCCN5C(=O)[C@H](CC(N)=O)NC1=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CSSSSC[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N4)NC3=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CSSSSC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCN=C(N)N)NC1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N2)C(C)C)[C@@H](C)O

InChI Key InChIKey=ZLKHOOSBNUOOBR-UHFFFAOYSA-N

Data  1 IC50  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50144882   

TargetMelanocortin receptor 4(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50144882(CHEMBL266288)
Affinity DataEC50:  9.40nMAssay Description:Effective concentration against mouse melanocortin MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50144882(CHEMBL266288)
Affinity DataIC50: 5.48nMAssay Description:Inhibitory concentration towards melanocortin MC4 receptor by displacing radioligand [125I]-hAGRP(82-132)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50144882(CHEMBL266288)
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration against mouse Melanocortin 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50144882(CHEMBL266288)
Affinity DataKd:  1.26nMAssay Description:Effective concentration against mouse Melanocortin 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed