BDBM50145099 CHEMBL3763243

SMILES O=c1[nH]nc2C(C(Nc3cccc1c23)c1ccc(CN2CCC2)cc1)c1ccccc1

InChI Key InChIKey=DDDWCXKAHSQDHC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145099   

TargetPoly [ADP-ribose] polymerase 1(Human)
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145099(CHEMBL3763243)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145099(CHEMBL3763243)
Affinity DataEC50:  9.70nMAssay Description:Inhibition of PARP in human LoVo cells assessed as inhibition of poly(ADP)-ribose polymerization for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed