BDBM50145101 CHEMBL3763674

SMILES Fc1ccc(cc1)C1C(Nc2cccc3c2c1n[nH]c3=O)c1ccc(CN2CCC2)cc1

InChI Key InChIKey=UMTZOWPWZLHANK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145101   

TargetPoly [ADP-ribose] polymerase 1(Human)
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145101(CHEMBL3763674)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145101(CHEMBL3763674)
Affinity DataEC50:  3.80nMAssay Description:Inhibition of PARP in human LoVo cells assessed as inhibition of poly(ADP)-ribose polymerization for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed