BDBM50145148 CHEMBL3764990

SMILES Cn1ccnc1[C@H]1[C@@H](Nc2cccc3c2c1n[nH]c3=O)c1ccc(F)cc1

InChI Key InChIKey=SOMLCVOFFCJGNU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145148   

TargetPoly [ADP-ribose] polymerase 1(Human)
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145148(CHEMBL3764990)
Affinity DataEC50:  285nMAssay Description:Inhibition of PARP in human LoVo cells assessed as inhibition of poly(ADP)-ribose polymerization for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Biomarin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50145148(CHEMBL3764990)
Affinity DataIC50: 136nMAssay Description:Inhibition of human PARP1 using [3H]NAD as substrate after 1 min by microplate scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2017
Entry Details Article
PubMed