BDBM50145432 CHEMBL3764563

SMILES COc1ccc(cc1)S(=O)(=O)NCc1cn(C[C@H]2CC=C(C(C)C)[C@@]22CCC(=O)C=C2)nn1

InChI Key InChIKey=FPEBEYJKVPVBKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145432   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50145432(CHEMBL3764563)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin) using cortisol as substrate assessed as NADPH formation by fluorescent plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50145432(CHEMBL3764563)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of full length human 11beta-HSD2 expressed in HEK293 cells using cortisone as substrate incubated for 2 hrs by HTRF assay in presence of N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed