BDBM50145444 CHEMBL3763187

SMILES [#6]-[#6](-[#6])-[#6]1=[#6]-[#6]-[#6@H](-[#6](=O)-[#7]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])[C@]11[#6]-[#6]-[#6](=O)-[#6]=[#6]1

InChI Key InChIKey=JGVKFEBNKFSQSO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145444   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50145444(CHEMBL3763187)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of 11beta-HSD1 (unknown origin) using cortisol as substrate assessed as NADPH formation by fluorescent plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50145444(CHEMBL3763187)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of full length human 11beta-HSD2 expressed in HEK293 cells using cortisone as substrate incubated for 2 hrs by HTRF assay in presence of N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed