BDBM50146344 CHEMBL330713::Dimethyl-[(3aS,12bS)-1-(2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-yl)methyl]-amine

SMILES CN(C)CC1C[C@@H]2[C@H](O1)c1ccccc1Oc1ccccc21

InChI Key InChIKey=KUCRPWOVGMMXDP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146344   

TargetHistamine H1 receptor(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146344(Dimethyl-[(3aS,12bS)-1-(2,3,3a,12b-tetrahydro-1,8-...)
Affinity DataKi:  33nMAssay Description:Ability to displace [3H]pyrilamine from human cloned histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Rat)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146344(Dimethyl-[(3aS,12bS)-1-(2,3,3a,12b-tetrahydro-1,8-...)
Affinity DataKi:  88nMAssay Description:In vitro binding affinity against norepinephrine transporter using [3H]-nisoxetine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146344(Dimethyl-[(3aS,12bS)-1-(2,3,3a,12b-tetrahydro-1,8-...)
Affinity DataKi:  93nMAssay Description:Ability to displace [125I]R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146344(Dimethyl-[(3aS,12bS)-1-(2,3,3a,12b-tetrahydro-1,8-...)
Affinity DataKi:  183nMAssay Description:Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed