BDBM50146358 4-Phenyl-1-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H-1-oxa-dibenzo[e,h]azulen-2-yl)methyl]-piperidine::CHEMBL96471

SMILES C(C1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21)N1CCC(CC1)c1ccccc1

InChI Key InChIKey=NTBSVMCWAHSWAK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50146358   

TargetHistamine H1 receptor(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146358(4-Phenyl-1-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H...)
Affinity DataKi:  30nMAssay Description:Ability to displace [3H]pyrilamine from human cloned histamine H1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146358(4-Phenyl-1-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H...)
Affinity DataKi:  43nMAssay Description:Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50146358(4-Phenyl-1-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H...)
Affinity DataKi:  1.09E+3nMAssay Description:Ability to displace [125I]R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed