BDBM50146587 CHEMBL3764571

SMILES FC(F)(F)c1cc(ccc1Cl)C(=O)Nc1cccc(c1)-c1cnc2c(NC(=O)c3cc(Cl)cc(Cl)c3)nccn12

InChI Key InChIKey=ZZSMAQLIEZGUAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146587   

TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146587(CHEMBL3764571)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50146587(CHEMBL3764571)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of wild-type B-Raf (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed