BDBM50146930 CHEMBL3764641

SMILES CN(C)C(=O)c1ccc(Oc2ccc(\C=C3/SC(=S)N(C3=O)c3ccc(OCCCN4CCN(C)CC4)cc3)cc2)cc1

InChI Key InChIKey=VNQDDDXWQSBTRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50146930   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
The Catholic University of Korea

Curated by ChEMBL
LigandPNGBDBM50146930(CHEMBL3764641)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of IKKbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2017
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Mouse)
The Catholic University of Korea

Curated by ChEMBL
LigandPNGBDBM50146930(CHEMBL3764641)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of IKKbeta in primary type-2 collagen immunized mouse splenocytes assessed as inhibition of TNFalpha production at 10 uM after 72 hrs by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2017
Entry Details Article
PubMed