BDBM50147497 3-Hydroxy-4-oxo-4H-pyran-2,6-dicarboxylic acid diethyl ester::CHEMBL110021

SMILES CCOC(=O)c1cc(=O)c(O)c(o1)C(=O)OCC

InChI Key InChIKey=CWZGQDOSIVDCEJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147497   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50147497(3-Hydroxy-4-oxo-4H-pyran-2,6-dicarboxylic acid die...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory potency of compound in presence of Mg2+ ion against NS5B HCV polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50147497(3-Hydroxy-4-oxo-4H-pyran-2,6-dicarboxylic acid die...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory potency against NS5B HCV polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50147497(3-Hydroxy-4-oxo-4H-pyran-2,6-dicarboxylic acid die...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory potency against NS5B HCV polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed