BDBM50147498 3-Hydroxy-4-oxo-4H-pyran-2,6-dicarboxylic acid 6-ethyl ester::CHEMBL109569

SMILES CCOC(=O)c1cc(=O)c(O)c(o1)C(O)=O

InChI Key InChIKey=MEUFIPDIZUSGJE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50147498   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50147498(3-Hydroxy-4-oxo-4H-pyran-2,6-dicarboxylic acid 6-e...)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibitory potency against NS5B HCV polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50147498(3-Hydroxy-4-oxo-4H-pyran-2,6-dicarboxylic acid 6-e...)
Affinity DataIC50: 650nMAssay Description:Inhibitory potency of compound in presence of Mn2+ ion against NS5B HCV polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50147498(3-Hydroxy-4-oxo-4H-pyran-2,6-dicarboxylic acid 6-e...)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibitory potency against NS5B HCV polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50147498(3-Hydroxy-4-oxo-4H-pyran-2,6-dicarboxylic acid 6-e...)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Mrl Rome

Curated by ChEMBL
LigandPNGBDBM50147498(3-Hydroxy-4-oxo-4H-pyran-2,6-dicarboxylic acid 6-e...)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of Hepatitis C virus NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed