BDBM50147843 (E)-3-[(3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidin-3-yl]-acrylic acid methyl ester::CHEMBL103191

SMILES COC(=O)\C=C\[C@H]1CN(C)CC[C@@H]1c1ccc(Cl)cc1

InChI Key InChIKey=PYSPNZYJFHNGTR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50147843   

TargetSodium-dependent dopamine transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147843((E)-3-[(3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperi...)
Affinity DataKi:  53nMAssay Description:Ability to inhibit high affinity uptake of [3H]DA at Dopamine transporter (DAT) using rat brain striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147843((E)-3-[(3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperi...)
Affinity DataKi:  272nMAssay Description:Ability to inhibit high affinity uptake of [3H]NE at Norepinephrine transporter (NET) using rat brain parietal/occipital cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147843((E)-3-[(3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperi...)
Affinity DataKi:  501nMAssay Description:Ability to inhibit high affinity uptake of [3H]-5-HT at Serotonin transporter (SERT) using rat midbrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed