BDBM50147844 Acetic acid (3R,4S)-4-(4-chloro-phenyl)-1-methyl-piperidin-3-ylmethyl ester::CHEMBL101431

SMILES CN1CC[C@@H]([C@@H](COC(C)=O)C1)c1ccc(Cl)cc1

InChI Key InChIKey=HJKKWIJTYBPLCJ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50147844   

TargetTransporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147844(Acetic acid (3R,4S)-4-(4-chloro-phenyl)-1-methyl-p...)
Affinity DataKi:  235nMAssay Description:Ability to inhibit high affinity uptake of [3H]NE at Norepinephrine transporter (NET) using rat brain parietal/occipital cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50147844(Acetic acid (3R,4S)-4-(4-chloro-phenyl)-1-methyl-p...)
Affinity DataIC50: 461nMAssay Description:Ability to displace [3H]WIN-35428 binding to dopamine transporter from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50147844(Acetic acid (3R,4S)-4-(4-chloro-phenyl)-1-methyl-p...)
Affinity DataKi:  599nMAssay Description:Ability to inhibit high affinity uptake of [3H]DA at Dopamine transporter (DAT) using rat brain striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50147844(Acetic acid (3R,4S)-4-(4-chloro-phenyl)-1-methyl-p...)
Affinity DataKi:  901nMAssay Description:Ability to inhibit high affinity uptake of [3H]-5-HT at Serotonin transporter (SERT) using rat midbrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed