BDBM50148027 CHEMBL3765705::US20240287089, Compound LMP517

SMILES OCCNCCCn1c2-c3cc4OCOc4cc3C(=O)c2c2ccc(F)cc2c1=O

InChI Key InChIKey=YFHMWOJCGJARKT-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148027   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50148027(CHEMBL3765705 | US20240287089, Compound LMP517)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine (N14Y) as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50148027(CHEMBL3765705 | US20240287089, Compound LMP517)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of recombinant human TDP2 using alpha32P-cordycepin-30-labeled 19-mer single-stranded oligonucleotide DNA containing 5'-phosphotyrosine (Y...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetMyc proto-oncogene protein(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM50148027(CHEMBL3765705 | US20240287089, Compound LMP517)
Affinity DataKd:  109nMAssay Description:MycG4 Stabilization Measured by FRET Melting. A F rster Resonance Energy Transfer (FRET)-melting assay was conducted in order to determine whether th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2024
Entry Details
Go to US Patent