BDBM50148104 2-Ethyl-7-[3-(4-phenoxy-phenoxy)-propoxy]-chroman-2-carboxylic acid::CHEMBL419019

SMILES CCC1(CCc2ccc(OCCCOc3ccc(Oc4ccccc4)cc3)cc2O1)C(O)=O

InChI Key InChIKey=HSKSXVIDFRFRQN-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148104   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148104(2-Ethyl-7-[3-(4-phenoxy-phenoxy)-propoxy]-chroman-...)
Affinity DataEC50:  220nMAssay Description:In vitro potency of PPAR gene activation against human Peroxisome proliferator activated receptor alpha using chimeric Gal4-hPPAR transactivation ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148104(2-Ethyl-7-[3-(4-phenoxy-phenoxy)-propoxy]-chroman-...)
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro binding affinity for human peroxisome proliferator activated receptor alpha using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148104(2-Ethyl-7-[3-(4-phenoxy-phenoxy)-propoxy]-chroman-...)
Affinity DataEC50:  1.00E+4nMAssay Description:In vitro transcriptional activation by human PPAR gamma Gal4 chimeraMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148104(2-Ethyl-7-[3-(4-phenoxy-phenoxy)-propoxy]-chroman-...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity for human peroxisome proliferator activated receptor gamma using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed