BDBM50148105 2-Ethyl-7-{3-[4-(4-methoxy-phenoxy)-2-propyl-phenoxy]-propoxy}-chroman-2-carboxylic acid::CHEMBL107991

SMILES CCCc1cc(Oc2ccc(OC)cc2)ccc1OCCCOc1ccc2CCC(CC)(Oc2c1)C(O)=O

InChI Key InChIKey=MBRSLMALLOBAEB-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148105   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148105(2-Ethyl-7-{3-[4-(4-methoxy-phenoxy)-2-propyl-pheno...)
Affinity DataIC50: 630nMAssay Description:In vitro binding affinity for human peroxisome proliferator activated receptor gamma using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148105(2-Ethyl-7-{3-[4-(4-methoxy-phenoxy)-2-propyl-pheno...)
Affinity DataEC50:  890nMAssay Description:In vitro potency of PPAR gene activation against human PPAR gamma receptor using chimeric Gal4-hPPAR transactivation assay (TA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148105(2-Ethyl-7-{3-[4-(4-methoxy-phenoxy)-2-propyl-pheno...)
Affinity DataEC50:  4.60E+3nMAssay Description:In vitro potency of PPAR gene activation against human Peroxisome proliferator activated receptor alpha using chimeric Gal4-hPPAR transactivation ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148105(2-Ethyl-7-{3-[4-(4-methoxy-phenoxy)-2-propyl-pheno...)
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity for human peroxisome proliferator activated receptor alpha using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed