BDBM50148169 (4-Chloro-phenyl)-[4-(4-methoxy-pyridin-2-ylamino)-piperidin-1-yl]-methanone::(4-chlorophenyl)(4-(4-methoxypyridin-2-ylamino)piperidin-1-yl)methanone::CHEMBL112866

SMILES COc1ccnc(NC2CCN(CC2)C(=O)c2ccc(Cl)cc2)c1

InChI Key InChIKey=NEWSIMOBDLUORJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148169   

TargetNitric oxide synthase, inducible(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148169((4-chlorophenyl)(4-(4-methoxypyridin-2-ylamino)pip...)
Affinity DataIC50: 53nMAssay Description:Inhibition of iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148169((4-chlorophenyl)(4-(4-methoxypyridin-2-ylamino)pip...)
Affinity DataIC50: 53nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148169((4-chlorophenyl)(4-(4-methoxypyridin-2-ylamino)pip...)
Affinity DataIC50: 7.80E+3nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148169((4-chlorophenyl)(4-(4-methoxypyridin-2-ylamino)pip...)
Affinity DataIC50: 3.60E+4nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed