BDBM50148240 CHEMBL3763271

SMILES COc1ccc(C2=NN(C3CCCCCC3)C(=O)[C@@H]3CC=CC[C@H]23)cc1OCCCCOc1ccc(C(=O)O)cc1

InChI Key InChIKey=NZTAZJDYGSXAMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148240   

LigandChemical structure of BindingDB Monomer ID 50148240BDBM50148240(CHEMBL3763271)
Affinity DataIC50: 0.316nMAssay Description:Inhibition of full length human recombinant PDE4B1 using [3H]-cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma brucei)
Mercachem

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148240BDBM50148240(CHEMBL3763271)
Affinity DataIC50: 316nMAssay Description:Inhibition of recombinant Trypanosoma brucei PDEB1 using [3H]-cAMP as substrate after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148240BDBM50148240(CHEMBL3763271)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of DNMT3A (unknown origin) using [3H]-SAM as substrate incubated for 1 hr by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed