BDBM50148317 2-(4-Hydroxy-phenyl)-2,5,6,7,8,9-hexahydro-pyrazolo[4,3-c]quinolin-3-one::CHEMBL324134

SMILES O=c1n([nH]c2c3CCCCc3ncc12)-c1ccccn1

InChI Key InChIKey=SNVPXIXZYAZTLO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148317   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148317(2-(4-Hydroxy-phenyl)-2,5,6,7,8,9-hexahydro-pyrazol...)
Affinity DataKi:  0.570nMAssay Description:In vitro binding affinity against gamma-aminobutyric acid A receptor, alpha 1 expressed in L(tk) cells by displacement of [3H]Ro-151788More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148317(2-(4-Hydroxy-phenyl)-2,5,6,7,8,9-hexahydro-pyrazol...)
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity against Gamma-aminobutyric acid A receptor, alpha 3 expressed in L(tk) cells by displacement of [3H]Ro-151788More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed