BDBM50148321 2-(4-Chloro-phenyl)-2,5a,6,7,8,9,10,10a-octahydro-5H-1,2,5-triaza-cyclohepta[e]inden-3-one::CHEMBL113659

SMILES Clc1ccc(cc1)-n1[nH]c2C3CCCCCC3N=Cc2c1=O

InChI Key InChIKey=PCEHLVFMKNNXOA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148321   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148321(2-(4-Chloro-phenyl)-2,5a,6,7,8,9,10,10a-octahydro-...)
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity against gamma-aminobutyric acid A receptor, alpha 1 expressed in L(tk) cells by displacement of [3H]Ro-151788More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148321(2-(4-Chloro-phenyl)-2,5a,6,7,8,9,10,10a-octahydro-...)
Affinity DataKi:  4.30nMAssay Description:In vitro binding affinity against Gamma-aminobutyric acid A receptor, alpha 3 expressed in L(tk) cells by displacement of [3H]Ro-151788More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed