BDBM50148328 2-(4-Cyclopropoxy-phenyl)-2,5,6,7,8,9-hexahydro-pyrazolo[4,3-c]quinolin-3-one::CHEMBL446673

SMILES O=c1n([nH]c2c3CCCCc3ncc12)-c1ccc(OC2CC2)cc1

InChI Key InChIKey=QQEUFIYKXLFBML-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148328   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148328(2-(4-Cyclopropoxy-phenyl)-2,5,6,7,8,9-hexahydro-py...)
Affinity DataKi:  1.10nMAssay Description:In vitro binding affinity against gamma-aminobutyric acid A receptor, alpha 1 expressed in L(tk) cells by displacement of [3H]Ro-151788More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148328(2-(4-Cyclopropoxy-phenyl)-2,5,6,7,8,9-hexahydro-py...)
Affinity DataKi:  2.20nMAssay Description:In vitro displacement of [3H]Ro-151788 from human GABA-A receptor alpha-3-beta-3-gamma-2 subunits expressed in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed