BDBM50148379 4-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naphthalen-1-ol::CHEMBL332097

SMILES CNCC[C@H](Oc1ccc(O)c2ccccc12)c1cccs1

InChI Key InChIKey=DRRXQCXSBONKPD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148379   

TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148379(4-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  63.9nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporter; Average of two experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148379(4-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  97.1nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148379(4-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  130nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporter; Average of two experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed