BDBM50148830 CHEMBL3770981

SMILES CCOC(=O)c1cccc(NC2=NC(=NC3(CCCCC3)N2)N(C)C)c1

InChI Key InChIKey=XMHPSFHTLVKATH-UHFFFAOYSA-N

Data  11 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50148830   

Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50148830(CHEMBL3770981)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]LSD from 5-HT2B receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50148830(CHEMBL3770981)
Affinity DataKi:  116nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50148830(CHEMBL3770981)
Affinity DataIC50: 285nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) expressed in CHO-K1 cells assessed as calcium flux after 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50148830(CHEMBL3770981)
Affinity DataKi:  516nMAssay Description:Displacement of [3H]LSD from 5-HT7A receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50148830(CHEMBL3770981)
Affinity DataKi:  595nMAssay Description:Displacement of [3H]LSD from 5-HT5A receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50148830(CHEMBL3770981)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]LSD from 5-HT2C receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50148830(CHEMBL3770981)
Affinity DataKi:  1.54E+3nMAssay Description:Displacement of [3H]Ketanserin from 5-HT2A receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50148830(CHEMBL3770981)
Affinity DataKi:  3.83E+3nMAssay Description:Displacement of [3H]GR127543 from 5-HT1D receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50148830(CHEMBL3770981)
Affinity DataKi:  4.78E+3nMAssay Description:Displacement of [3H]LSD from 5-HT6 receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50148830(CHEMBL3770981)
Affinity DataKi:  9.65E+3nMAssay Description:Displacement of [3H]GR127543 from 5-HT1B receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50148830(CHEMBL3770981)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LY278584 from 5-HT3 receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50148830(CHEMBL3770981)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-5-HT from 5-HT1E receptor (unknown origin) after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed