BDBM50148892 Butyl-ethyl-[2,3,6-trimethyl-1-(2,4,6-trimethyl-phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-amine::CHEMBL333713

SMILES CCCCN(CC)c1cc(C)nc2n(c(C)c(C)c12)-c1c(C)cc(C)cc1C

InChI Key InChIKey=MULBKUIZDWUGKN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148892   

TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50148892(Butyl-ethyl-[2,3,6-trimethyl-1-(2,4,6-trimethyl-ph...)
Affinity DataIC50: 16nMAssay Description:Inhibition of CRF-stimulated cAMP production in cells expressing CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50148892(Butyl-ethyl-[2,3,6-trimethyl-1-(2,4,6-trimethyl-ph...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity to the cloned human corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50148892(Butyl-ethyl-[2,3,6-trimethyl-1-(2,4,6-trimethyl-ph...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed