BDBM50149156 CHEMBL3771094

SMILES Nc1cc(c(cn1)-c1nc(N2CCOCC2)c2ccc(NC(=O)c3ccncc3)cc2n1)C(F)(F)F

InChI Key InChIKey=HFCUOGDBTTWZPG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50149156   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50149156(CHEMBL3771094)Copy SMILESCopy InChI

Affinity DataIC50: 419nMAssay Description:Inhibition of PI3K alpha (unknown origin) using PIP2 as substrate after 1 hr by kinase-Glo luminescent assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/23/2017
Entry Details Article
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