BDBM50149342 4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]quinoline-8-carboxylic acid ethyl ester::CHEMBL118389

SMILES CCOC(=O)c1ccc2N3CCC(=O)C(C)=C3CCc2c1

InChI Key InChIKey=VBDHAMXHEONACP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149342   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50149342(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50: 221nMAssay Description:Inhibitory concentration against human recombinant steroid 5-alpha-reductase type I in stably transfected chinese hamster ovary (CHO) 1827 cells usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50149342(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50: 221nMAssay Description:Inhibitory concentration against human steroid 5-alpha-reductase I receptor expressed in CHO 1827 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
Polo Scientifico Università

Curated by ChEMBL
LigandPNGBDBM50149342(4-Methyl-3-oxo-2,3,5,6-tetrahydro-1H-pyrido[1,2-a]...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibitory concentration against human steroid 5-alpha-reductase 2 receptor expressed in CHO 1829 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed